Yes, they do. There are several lines going to Santiago and La Cola de Caballo leaving from the Central in Monterrey. It depends on the service you want to get. You can also can take those buses along Madero St or Felix U, Gomez St in downtown. If you are in Monterrey over the weekendm you might be able to get direct bus to la Cola de Caballo leaving from the Central or La Alameda.
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