Check the SNFC site. There are high speed trains from CDG that go to Lyon, and also from Paris leaving the Gare de Lyon station. Depending on your need you may want to order a travel pass for the number of travel days you are going, then all you need to do is make the reservations. It seemed like the train between CDG / Paris and Lyon was fairly popular as we could not change our reservations to an earlier train on the same day. We could have had we booked the day before.
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