The city center is only about 2 km to the border (Aflao in Ghana), take a taxi to the border, cross it (you need to get the Ghana visa before, in the other direction the Togo visa you can get there), just after the border are some taxis and minibuses (leaving when full, a bit overpriced), walk 100 meter further to the bus station, you find frequent buses from there.
Be the first to rate this answer!