I know there is a shuttle service from Granada to Managua that costs about 15USD so there should be one going to Granada as well. Unfortunately, I can't remember which company it was with. You can take a cab and it will cost about 30USD (ride is 45-1hr). I arranged my cab through the volunteer organization I was with, but I'm sure you can just take a cab that's at the airport - make sure to confirm price beforehand! There are also buses that will take you pretty much near the centre of town. Hope this helps and enjoy Granada!
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