Well not sure if Antigua is "special" in these matters, and it is not just regarding departure from there. Swabing is a way of life in many airports, and certainly in American ones.
What it means is not the CSI type of a DNA swab from inside the mouth. What an airport security swab means is that they sometimes swab your bags, and it is put in a shoebox size scanner, which scans for explosives residue, they also sometimes swab a person's hands for the same reason.
This is only done on people that are pulled aside for a thorough scans. Here is some tips that are devised by the TSA, for easy security checks. Travellers are encouraged to know what to do to make the process easier.
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